Welcome to rezvanilab in Berlin!

Our lab develops strategies for in vivo liver tissue regeneration and studies complex organ development in blood-liver organoids.

The Rezvani lab at Charité University Medicine Berlin–a team of biologists and clinician-scientists–aims to identify new signals that can restore normal liver function and encourage regeneration in cases of chronic injuries.

To achieve this, we create innovative human organoids with a syngeneic immune system to reverse-engineer inter-lineage pathophysiologies since many chronic liver diseases are caused or influenced by inflammation. Other “tools” involve humanized mice, CRISPR screens and more…

Our ultimate goal is to develop RNA-based therapies that can treat fibro-inflammatory processes in children and adults with chronic liver diseases by targeting chronically injured liver cells.