rezvani lab @ Charité
re: programming liver fibrosis in vivo
re: storing healthy hepatocyte networks and function in situ
re: capitulating multicellular crosstalk in injury and development in organoids
German Research Foundation (DFG) Project No. 437638965: “Healing from within – Establishing a code to create therapeutic human hepatocytes in situ.”
The Rezvani Lab has opened its doors in the Charité – Department of Pediatrics, Division of Gastroenterology, Nephrology and Metabolic Medicine. The lab is primarily funded by the DFG – Emmy Noether Program.
The overarching goal of the Rezvani lab is to identify novel signals to regenerate diseased livers on a transcriptional, complex-cellular and tissue level. Via complex human organoid systems and liver-humanized (chimeric) mice, this information will be harnessed to establish in vivo hepatic reprogramming as a novel treatment strategy for fibro-inflammatory processes in chronic liver diseases of children and adults.